Acetyl L-Carnitine 500mg Capsules
Acetyl L-Carnitine 500mg Capsules (100 Capsules)
$14.53 - $15.29
A natural fat burner, antioxidant, and nootropic!*
Quantity Discount Price
1-4
$0.00
$15.29
5+
5%
$14.53
SKU: 4019

Acetyl L-Carnitine (ALCAR) is a modified (acetylated) form of L-Carnitine, a nitrogen-containing compound derived from L-Lysine.  The carnitine molecule is necessary for the proper movement of fat molecules into the mitochondria for oxidation (fat burning).  It seems to be beneficial for individuals suffering from a large array of maladies, including anorexia, chronic fatigue, coronary vascular disease, diphtheria, hypoglycemia, male infertility, muscular myopathies, Rett syndrome, as well as preterm infants, dialysis patients, and HIV+ individuals(1)  ALCAR also seems to be very useful for age-associated cognitive impairment, such as Alzheimer’s(2).

A controversial supplement for many years, its effect on exercise performance has not been established(3).  Similarly, studies examining the effect of ALCAR on fat oxidation have been mixed, with some studies showing a beneficial, lipolytic effect(4), and others showing no effect(5, 6), or even a shift toward greater carbohydrate (less fat) oxidation(7).  Animal studies suggest a nitrogen sparing effect of L-Carnitine during fasting(8), but a study of humans undergoing a calorically restrictive diet and exercise program found no effect(9).  However, individuals with impaired muscle performance (possibly suggestive of deficiency) may benefit from L-Carnitine supplementation.  A study by Pistone et al. (10) found that older individuals with highly fatigable muscles increased muscle mass, lost body fat, improved muscular performance and their blood lipid profiles simply by supplementing with L-Carnitine. 

Suggested Use

As a dietary supplement, take 1 Serving (1 capsule) 1 to 3 times daily. 

Ingredients

Active Ingredients

Acetyl L-Carnitine.

Inactive Ingredients

Rice Concentrate, Magnesium Stearate, Capsule (Vegetable Cellulose).

General Warnings

If you are currently pregnant or nursing, consult a physician prior to use. Keep out of the reach of children.

Allergen Warnings

This product is free from all forms of shell fish, tree nuts, yeast, gluten, salt, preservatives, lactose, and soy. This product is manufactured in a facility that handles soy, gluten, and milk products. Products ordered using Premium Flavor Systems will contain artificial flavoring and sweeteners. This product is manufactured in a facility that handles milk, soy, egg, peanut, nut, tree, fish, crustaceans/shellfish, and wheat products. 

DISCLAIMER: The above description is provided for information only and does not constitute medical advice.  Please consult your physician or the appropriately licensed professional before engaging in a program of exercise or nutritional supplementation.  No information in this site has been reviewed by the FDA.  No product is intended to treat, diagnose, or cure any disease.  

References

1. Kelly, G.S., L-Carnitine: therapeutic applications of a conditionally-essential amino acid. Altern Med Rev, 1998. 3(5): p. 345-60. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=9804680

2. Montgomery, S.A., et al., Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease. Int Clin Psychopharmacol, 2003. 18(2): p. 61-71. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12598816

3. Brass, E.P., Carnitine and sports medicine: use or abuse? Ann N Y Acad Sci, 2004. 1033: p. 67-78. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15591004

4. Wutzke, K.D. and H. Lorenz, The effect of l-carnitine on fat oxidation, protein turnover, and body composition in slightly overweight subjects. Metabolism, 2004. 53(8): p. 1002-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15281008

5. Broad, E.M., et al., Effects of four weeks L-carnitine L-tartrate ingestion on substrate utilization during prolonged exercise. Int J Sport Nutr Exerc Metab, 2005. 15(6): p. 665-79. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16521850

6. Decombaz, J., et al., Effect of L-carnitine on submaximal exercise metabolism after depletion of muscle glycogen. Med Sci Sports Exerc, 1993. 25(6): p. 733-40. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8321112

7. Abramowicz, W.N. and S.D. Galloway, Effects of acute versus chronic L-carnitine L-tartrate supplementation on metabolic responses to steady state exercise in males and females. Int J Sport Nutr Exerc Metab, 2005. 15(4): p. 386-400. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16286670

8. Heo, K., et al., Dietary L-carnitine improves nitrogen utilization in growing pigs fed low energy, fat-containing diets. J Nutr, 2000. 130(7): p. 1809-14. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10867055

9. Villani, R.G., et al., L-Carnitine supplementation combined with aerobic training does not promote weight loss in moderately obese women. Int J Sport Nutr Exerc Metab, 2000. 10(2): p. 199-207. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10861338

10. Pistone, G., et al., Levocarnitine administration in elderly subjects with rapid muscle fatigue: effect on body composition, lipid profile and fatigue. Drugs Aging, 2003. 20(10): p. 761-7. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12875611

11. Rebouche, C.J., Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism. Ann N Y Acad Sci, 2004. 1033: p. 30-41. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15591001

12. Ames, B.N. and J. Liu, Delaying the mitochondrial decay of aging with acetylcarnitine. Ann N Y Acad Sci, 2004. 1033: p. 108-16. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15591008

 


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